Efectos de la melatonina en el tratamiento de enfermedades cardiovasculares: avances del último año



Numerosos estudios han sugerido que la melatonina tiene un papel importante en varias enfermedades cardiovasculares. Los estudios examinados en este documento científico, han demostrado que la melatonina tiene efectos significativos en el daño por isquemia-reperfusión,  hipertensión pulmonar, hipertensión, enfermedades de la válvula cardíaca , enfermedades vasculares y en el metabolismo de los lípidos. La melatonina puede ser una nueva opción terapéutica para el tratamiento de enfermedades cardiovasculares.

Effects of melatonin on cardiovascular diseases: progress in the past year.
Curr Opin Lipidol. 2016 Apr 12;
Authors: Sun H, Gusdon AM, Qu S

Abstract
PURPOSE OF REVIEW: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland. Numerous studies have suggested that melatonin plays an important role in various cardiovascular diseases. In this article, recent progress regarding melatonin's effects on cardiovascular diseases is reviewed.
RECENT FINDINGS: In the past year, studies have focused on the mechanism of protection of melatonin on cardiovascular diseases, including myocardial ischemia-reperfusion injury, myocardial hypoxia-reoxygenation injury, pulmonary hypertension, hypertension, atherosclerosis, valvular heart diseases, and other cardiovascular diseases.
SUMMARY: Studies have demonstrated that melatonin has significant effects on ischemia-reperfusion injury, myocardial chronic intermittent hypoxia injury, pulmonary hypertension, hypertension, valvular heart diseases, vascular diseases, and lipid metabolism. As an inexpensive and well tolerated drug, melatonin may be a new therapeutic option for cardiovascular disease.

PMID: 27075419 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/27075419?dopt=Abstract




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