Eficacia de la melatonina en la prevención, tratamiento y gestión del delirio y demencia senil

Estudios clínicos recientes demuestran que la melatonina puede ser útil en la prevención, el tratamiento del delirio y en  la gestión de la demencia senil.

Melatonin based therapies for delirium and dementia.

Discov Med. 2016 May;21(117):363-371

Authors: Alagiakrishnan K

Abstract
Melatonin levels have been shown to decline with aging. Melatonin and its analogs in addition to their effect on sleep promotion, has been shown to have multiple pleiotropic effects. It can also help with neuroprotection through different mechanisms. Evidence in animal and human studies suggests that low levels of melatonin have been linked to delirium, mild cognitive impairment, dementia, and with certain behavioral problems. Recent clinical trials have showed that both melatonin and its analogs may be useful in the prevention, treatment of delirium, and the management of dementia. These medications seem to have the advantage of less side effects and better safety profile when compared to antipsychotics and sedatives like benzodiazepines. These medications are available over the counter in North America, Europe, and Asia, and some of these medications are approved by FDA. This manuscript will discuss the promising role of these melatonergic medications alone or in combination with other medications for the management of Geriatric Psychiatric diseases like delirium and dementia.

PMID: 27355332 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/27355332?dopt=Abstract

Compra on line profesional. Farmacias, herbolarios, naturópatas y profesionales del sector.

Key Melatonin

www.melatonina.es